Please use this identifier to cite or link to this item: http://hdl.handle.net/10497/22105
Title: 
Authors: 
Issue Date: 
2019
Citation: 
Phyo, M. Y., Ding, C. Y. G., Goh, H. C., Goh, J. X., Ong, J. F. M., Chan, S. H., Yung, P. Y. M., Candra, H., & Tan, L. T. (2019). Trikoramide A, a prenylated cyanobactin from the marine cyanobacterium symploca hydnoides. Journal of Natural Products, 82(12), 3482-3488. https://doi.org/10.1021/acs.jnatprod.9b00675
Abstract: 
A new cyclic decapeptide, trikoramide A (1), has been isolated from samples of the marine cyanobacterium Symploca hydnoides, collected from Bintan Island, Indonesia. Trikoramide A (1) is a C-prenylated cyclotryptophan-containing cyanobactin. Its planar structure was deduced by 1D and 2D NMR spectroscopy as well as HR–MS/MS data. In addition, its absolute configuration was determined by Marfey’s method and 2D NOESY NMR spectroscopic analysis. Compound 1 possessed cytotoxicity against the MOLT-4 and AML2 cancer cell lines with IC50 values of 4.8 and 8.2 μM, respectively.
Description: 
This is the original draft, prior to peer-review, of a manuscript published in Journal of Natural Products. The published version is available online at https://doi.org/10.1021/acs.jnatprod.9b00675
URI: 
Website: 
Appears in Collections:Journal Articles

Files in This Item:
File Description SizeFormat 
JNP-82-12-3482.pdf473.6 kBAdobe PDFThumbnail
View/Open
Show full item record

Page view(s)

29
checked on Jul 12, 2020

Download(s)

10
checked on Jul 12, 2020

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.