Ligand-free CuCL-catalyzed N-arylation of 1,2,4-triazole with aryl bromides

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Citation
Ang, W., Low, C. K. Y., & Teo, Y.-C. (2024). Ligand-free CuCL-catalyzed N-arylation of 1,2,4-triazole with aryl bromides. Synlett, 35(7), 821-825. https://doi.org/10.1055/a-2229-1887
Author
Ang, Wei Zhi
•
Low, Chloe Kah Yee
•
Teo, Yong Chua 
Abstract
An efficient protocol was developed for the N-arylation of 1,2,4-triazoles using substituted aryl bromides catalyzed by CuCl under ligand-free conditions. This method afforded the products in good to excellent yields (up to 88%) under the optimized conditions.
Date Issued
2024
Publisher
Thieme
Journal
Synlett
DOI
10.1055/a-2229-1887